Choline

 

  

Although choline is not classed as a vitamin, it is an essential nutrient, and is usually grouped with the Bcomplex vitamins.

Food source for Choline:

Egg yolks, lecithin, legumes, yeast, liver, whole-grains, and milk. Choline is synthesized in the body by the interaction of B12, and folice acid with the amino acid methionine.

Functions of Choline:

Choline is involved in the transportation and metabolism of fats, it aids in hormone production and reduces excess fat in the liver. It is involved in the detoxification of chemicals, and the formation of acetycholine a neurotransmitter needed for the transmission of nerve impulses.

 Deficiency symptoms of Choline:

Choline deficiency is associated with fatty liver, bleeding stomach ulcers, cirrhosis, vascular damage, impaired immune response, athersclerosis, arterosclerosis, and hemorrhaging of kidneys.

Factors increasing the demand for Choline:

Alcohol, coffee, liver disease, impaired memory function, and  low protein diets.

Therapeutic use of Choline:

Tardive dyskinesia, this problem results from the use of psychiatric drugs interference with the neurotransmitter acetycholine. Huntington's disease, myasthenia gravis, ataxia, cancer, glaucoma, cancer, high blood pressure,  heart disease, depressive diseases, Tourette's sndrome, and Alzheimer's disease.

Drugs affecting Choline:

Alcohol, sulfa drugs, and estrogen.

Dosage and toxicity of Choline:

RDA 1gm. The average diet is estimated to contain enough choline, so supplementation is not usually required. High doses of choline may cause nausea, salivation, diarrhea, abdominal cramps, dizziness and depression. Because choline is synthesized in the body, it is usually understood that supplementation is not necessary. This may be the case in a healthy individual following a well balanced diet, however,  diets deficient in essential nutrients, with the added toxicity of drugs, either recreational or prescription may interfere with the absorption of choline.

Read more:Inositol

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